Highlighting selection

    function getCarData() {
      return [
["Tesla", 2017, "black", "black"],
["Nissan", 2018, "blue", "blue"],
["Chrysler", 2019, "yellow", "black"],
["Volvo", 2020, "white", "gray"]
      ];
    }

Use options currentRowClassName and currentColumnClassName

.currentRow {
  background-color: #F9F9FB !important;
}
.currentCol {
  background-color: #E7E8EF !important;
}
      

var
  data = [
    ['', 'Tesla', 'Nissan', 'Toyota', 'Honda'],
    ['2017', 10, 11, 12, 13],
    ['2018', 20, 11, 14, 13],
    ['2019', 30, 15, 12, 13]
  ],
  container = document.getElementById('example1'),
  hot;

hot = Handsontable(container, {
  data: data,
  minRows: 5,
  minCols: 6,
  currentRowClassName: 'currentRow',
  currentColClassName: 'currentCol',
  rowHeaders: true,
  colHeaders: true
});

hot.selectCell(2,2);